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Also known as High Pressure Liquid Chromatography, High Performance Liquid Chromatography (HPLC) is an essential sampling and measurement technique that allows for extremely accurate readings of the composition of mixtures. The technique is commonly found anywhere chemical analysis is needed, from medicine to law enforcement, and is typically a part of chemistry.

The method works by using pressurized solvents and sometimes head to separate compounds into their individual ingredients. It is sister to lower pressure chromatography, and the general utility of HPLC has made it an industry standard in many sectors.

As a role HPLC has a strong role in many pharmaceutical companies, especially in clinical research and manufacturing, particularly where quality control and quality assurance are concerned.  Specialists find a place at the lab bench, with responsibilities like testing for impurities and making routine assays. They may use their talents in every step of the manufacturing process, from testing raw ingredients to sampling the finished product at high enough volumes to confirm consumer safety and regulatory compliance.

Possible career paths with and HPLC specialization include:

  • Pharmaceutical Laboratory Technician
  • Quality Control and Assurance Analyst
  • Medical Manufacturing Quality Control Manager
  • Analytical Chemist
  • Associate Scientist
  • Research Quality Control
  • HPLC Analyst